📄 Description (English)
Vulnerability in the Oracle Life Sciences Empirica Signal product of Oracle Life Science Applications (component: Common Core). Supported versions that are affected are 9.2.1-9.2.3. Easily exploitable vulnerability allows low privileged attacker with network access via HTTP to compromise Oracle Life Sciences Empirica Signal. While the vulnerability is in Oracle Life Sciences Empirica Signal, attacks may significantly impact additional products (scope change). Successful attacks of this vulnerability can result in unauthorized creation, deletion or modification access to critical data or all Oracle Life Sciences Empirica Signal accessible data as well as unauthorized read access to a subset of Oracle Life Sciences Empirica Signal accessible data. CVSS 3.1 Base Score 8.5 (Confidentiality and Integrity impacts). CVSS Vector: (CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:C/C:L/I:H/A:N).
🤖 AI Executive Summary
CVE-2026-21997 is a high-severity vulnerability (CVSS 8.5) in Oracle Life Sciences Empirica Signal versions 9.2.1-9.2.3 that allows low-privileged attackers with network access to compromise the system via HTTP. The vulnerability enables unauthorized creation, deletion, or modification of critical data and unauthorized read access to sensitive information. With scope change implications affecting additional Oracle products, this poses significant risk to healthcare and pharmaceutical organizations in Saudi Arabia relying on Oracle Life Sciences solutions.
📄 Description (Arabic)
🤖 AI Intelligence Analysis Analyzed: Apr 24, 2026 02:50
🇸🇦 Saudi Arabia Impact Assessment
Healthcare sector organizations and pharmaceutical companies in Saudi Arabia using Oracle Life Sciences Empirica Signal are at highest risk. This includes hospitals, medical research institutions, and pharmaceutical manufacturers regulated by the Saudi Food and Drug Authority (SFDA). The vulnerability's scope change means potential lateral movement to other Oracle systems within healthcare IT infrastructure. Government health entities under the Ministry of Health and private healthcare providers are particularly vulnerable. The ability to modify critical healthcare data poses direct risks to patient safety and regulatory compliance with SFDA requirements.
🏢 Affected Saudi Sectors
Healthcare
Pharmaceutical Manufacturing
Medical Research Institutions
Government Health Entities
Private Healthcare Providers
Biotech Companies
Clinical Research Organizations
🎯 MITRE ATT&CK Techniques
T1190 - Exploit Public-Facing Application
T1078 - Valid Accounts
T1566 - Phishing
T1199 - Trusted Relationship
T1021 - Remote Services
T1040 - Traffic Sniffing
T1555 - Credentials from Password Stores
T1110 - Brute Force
T1098 - Account Manipulation
T1136 - Create Account
T1485 - Data Destruction
T1565 - Data Manipulation
T1041 - Exfiltration Over C2 Channel
T1020 - Automated Exfiltration
T1537 - Transfer Data to Cloud Account
⚖️ Saudi Risk Score (AI)
8.2
/ 10.0
🔧 Remediation Steps (English)
IMMEDIATE ACTIONS:
1. Identify all systems running Oracle Life Sciences Empirica Signal versions 9.2.1-9.2.3 in your environment
2. Restrict network access to affected systems to authorized users only; implement network segmentation
3. Enable HTTP request logging and monitor for suspicious low-privileged account activities
4. Review access logs for unauthorized data modifications or deletions in the past 30 days
PATCHING GUIDANCE:
5. Contact Oracle Support immediately to obtain available patches or workarounds (no patch currently available as of CVE publication)
6. Plan upgrade to patched version once available; test in non-production environment first
7. If patching is delayed, implement compensating controls: WAF rules to restrict HTTP access, IP whitelisting, VPN requirement for access
DETECTION & MONITORING:
8. Deploy IDS/IPS signatures to detect exploitation attempts targeting Oracle Life Sciences Empirica Signal
9. Monitor for HTTP requests with suspicious parameters targeting the Common Core component
10. Alert on any unauthorized data creation, deletion, or modification events in audit logs
11. Implement database activity monitoring (DAM) to track changes to critical healthcare data
12. Review user privilege assignments; ensure principle of least privilege is enforced
🔧 خطوات المعالجة (العربية)
الإجراءات الفورية:
1. تحديد جميع الأنظمة التي تقوم بتشغيل Oracle Life Sciences Empirica Signal الإصدارات 9.2.1-9.2.3 في بيئتك
2. تقييد الوصول إلى الأنظمة المتأثرة للمستخدمين المصرح لهم فقط؛ تنفيذ تقسيم الشبكة
3. تفعيل تسجيل طلبات HTTP ومراقبة الأنشطة المريبة للحسابات ذات الامتيازات المنخفضة
4. مراجعة سجلات الوصول للتعديلات أو الحذف غير المصرح به للبيانات في آخر 30 يوماً
إرشادات التصحيح:
5. الاتصال بدعم Oracle فوراً للحصول على التصحيحات المتاحة أو الحلول البديلة (لا يوجد تصحيح متاح حالياً)
6. التخطيط للترقية إلى الإصدار المصحح بمجرد توفره؛ الاختبار في بيئة غير الإنتاج أولاً
7. إذا تأخر التصحيح، تنفيذ الضوابط البديلة: قواعد WAF لتقييد الوصول HTTP، قائمة IP البيضاء، متطلبات VPN
الكشف والمراقبة:
8. نشر توقيعات IDS/IPS للكشف عن محاولات الاستغلال التي تستهدف Oracle Life Sciences Empirica Signal
9. مراقبة طلبات HTTP بمعاملات مريبة تستهدف مكون Common Core
10. التنبيه على أي أحداث إنشاء أو حذف أو تعديل بيانات غير مصرح به في سجلات التدقيق
11. تنفيذ مراقبة نشاط قاعدة البيانات (DAM) لتتبع التغييرات على بيانات الرعاية الصحية الحرجة
12. مراجعة تعيينات امتيازات المستخدم؛ التأكد من تطبيق مبدأ أقل امتياز
📋 Regulatory Compliance Mapping
🟢 NCA ECC 2024
A.5.1.1 - Information Security Policies and Procedures
A.6.1.1 - User Access Management
A.6.2.1 - User Access Rights Review
A.7.1.1 - Physical and Environmental Security
A.8.1.1 - Cryptography and Data Protection
A.9.1.1 - Access Control and Authentication
A.10.1.1 - Logging and Monitoring
A.12.4.1 - Event Logging
🔵 SAMA CSF
Governance & Risk Management - Risk Assessment and Management
Information & Cybersecurity - Data Protection and Privacy
Information & Cybersecurity - Access Control and Authentication
Resilience - Incident Detection and Response
Resilience - Monitoring and Logging
🟡 ISO 27001:2022
5.1 - Policies for information security
6.1 - Information security roles and responsibilities
6.2 - Information security competencies
7.1 - General requirements for information security
8.1 - User endpoint devices
8.2 - Privileged access rights
8.3 - Information access restriction
8.4 - Access to cryptographic keys
8.5 - Authentication
8.6 - Capacity management
8.7 - Protection against malware
8.8 - Management of removable media
8.9 - Removal of access rights
8.10 - Use of cryptography
8.11 - Physical and logical access control
8.12 - Configuration management
8.13 - Information deletion
8.14 - Data masking
8.15 - Data leakage prevention
8.16 - Monitoring
8.17 - Monitoring activities
8.18 - Removal of access rights
8.19 - Information security in supplier relationships
8.20 - Addressing information security in ICT supplier agreements
8.21 - Managing information security in ICT supply chain
8.22 - Monitoring, review and change management of supplier services
8.23 - Information security for use of cloud services
8.24 - Planning and preparing for information security incident handling and improvement
8.25 - Assessment and decision on information security events
8.26 - Response to information security incidents
8.27 - Learning from information security incidents
8.28 - Collecting evidence
8.29 - Improving information security incident handling processes
8.30 - Continuity planning
8.31 - Identifying and making decisions on information security continuity requirements
8.32 - Planning and implementing information security continuity
8.33 - Verification, review and evaluation of information security continuity
8.34 - Information security in change management
8.35 - Information security in project management
8.36 - Responsibility and authority for information security
8.37 - Information security in supplier relationships
8.38 - Monitoring and review of supplier information security practices
🟣 PCI DSS v4.0.1
Not directly applicable - Oracle Life Sciences Empirica Signal is not a payment processing system; however, if healthcare organizations process payments, Requirement 1 (Firewall Configuration), Requirement 2 (Default Passwords), Requirement 6 (Secure Development), Requirement 7 (Access Control), Requirement 8 (User Identification), Requirement 10 (Logging and Monitoring) may be indirectly affected
🔗 References & Sources 1